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Abstract #1585

Accuracy of quantitative DCE-MRI depends on the implementation of the convolution operation

Zaki Ahmed1,2 and Ives R. Levesque2,3
1Department of Radiology, Mayo Clinic, Rochester, MN, United States, 2Medical Physics Unit, McGill University, Montreal, QC, Canada, 3Research Institute of the McGill University Health Centre, Montreal, QC, Canada


Quantitative DCE-MRI analysis requires fitting a model to the acquired enhancing time-course data. These models involve a convolution operation, which has a variety of possible implementations. The goal of this work was to evaluate three different implementations of the convolution operation: (i) Fourier, (ii) Summation, (iii) Iterative. The accuracy and execution time of each implementation was compared on a virtual phantom. It was found that the iterative technique was the fastest while also having the best overall accuracy.

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