Abstract #1585

Accuracy of quantitative DCE-MRI depends on the implementation of the convolution operation

Zaki Ahmed^1,2 and Ives R. Levesque^2,3

¹Department of Radiology, Mayo Clinic, Rochester, MN, United States, ²Medical Physics Unit, McGill University, Montreal, QC, Canada, ³Research Institute of the McGill University Health Centre, Montreal, QC, Canada

Synopsis

Quantitative DCE-MRI analysis requires fitting a model to the acquired enhancing time-course data. These models involve a convolution operation, which has a variety of possible implementations. The goal of this work was to evaluate three different implementations of the convolution operation: (i) Fourier, (ii) Summation, (iii) Iterative. The accuracy and execution time of each implementation was compared on a virtual phantom. It was found that the iterative technique was the fastest while also having the best overall accuracy.

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