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Abstract #1602

MRI Relaxation Times Change in the Metaphysis Following Ischemic Injury to the Femoral Head: An In Vivo Piglet Model Study

Erick Buko1,2, Alexandra R Armstrong1, Ferenc Tóth1, and Casey P Johnson1,2
1Veterinary Clinical Sciences, University of Minnesota, ST. Paul, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States


Quantitative mapping of T2, T1ρ, adiabatic T1ρ, and adiabatic T2ρ relaxation times may be useful to assess ischemic injury to the femoral head. In this work, we investigated whether these relaxation times are sensitive in detecting compositional changes to the primary spongiosa (the region of the metaphysis adjacent to the growth plate) following ischemic injury to the femoral head in a piglet model. We found that T1ρ and adiabatic T2ρ decreased in the primary spongiosa following ischemic injury to the femoral epiphysis, which suggests these methods may be useful to assess femoral head growth disturbances following ischemic injury.

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