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Abstract #1621

Feasibility of 3D Adiabatic T-prepared Fast Spin Echo (3D Adiab-T-FSE) Imaging

Hyungseok Jang1, Yajun Ma1, Dina Moazamian1, Michael Carl2, Saeed Jerban1, Alecio F Lombardi1, Christine B Chung1,3, Eric Y Chang1,3, and Jiang Du1
1Radiology, University of California San Diego, San Diego, CA, United States, 2GE Healthcare, San Diego, CA, United States, 3Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, United States


T has been investigated as a quantitative biomarker sensitive to changes in macromolecules such as proteoglycan and collagen in musculoskeletal systems. More recently, adiabatic T (Adiab-T) has emerged as an alternative to conventional continuous wave T to reduce the magic angle effect, which is a major confounding factor in accurate T estimation. In this study, we investigated a new pulse sequence combining adiabatic T preparation and efficient 3D fast spin echo (FSE) for more robust adiab-T mapping in the human knee. The efficacies of RF cycling and magnetization reset were also demonstrated.

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