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Abstract #1622

Effects of T2*-blurring on effective resolution of diffusion MRI with spiral and EPI readout trajectories at 7T

Sajjad Feizollah1,2 and Christine L. Tardif1,2,3
1Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada, 2McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, QC, Canada, 3Department of Biomedical Engineering, McGill University, Montreal, QC, Canada


Several strategies have been used to increase the SNR of diffusion-weighted imaging including the use of partial Fourier EPI and spiral trajectories. Although these methods increase the SNR and sequence efficiency significantly, they affect the image quality and resulting diffusion measures causing loss of microstructural information of fine structures. Blurring caused by the T2* decay is one of the important effects resulting in low effective resolutions. Shorter T2* at ultra-high magnetic fields reduces the effective resolution in spite of providing higher SNR. This study shows about 60% lower effective resolution than the nominal resolution using PF-EPI and spiral at 7T.

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