Head-tilting in diffusion weighted imaging to reduce susceptibility-induced signal dropout in the frontal cortex: feasibility study.
Jae-Kyun Ryu1, Chuluunbaatar Otgonbaatar2, Seok-Jin Yeo3, Jeonghak Song4, Eunseok Jang4, Jaebin Lee4, and Hackjoon Shim1,4
1Medical Imaging AI Research Center, Canon Medical Systems Korea, Seoul, Korea, Republic of, 2Department of Radiology, Seoul National University, Seoul, Korea, Republic of, 3Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, 4Magnetic Resonance Business Unit, Canon Medical Systems Korea, Seoul, Korea, Republic of
Diffusion-weighted MRI is a highly sensitive to alteration in the movement of water molecules and allows the assessment of various pathologies. Interpretation of the changes can be obscured by signal-dropout due to tissue-air susceptibility difference at the boundaries of nasal cavities, especially in the prefrontal region. The head tilting (chin-up) method during the brain scan could be considered as an accessible way without additional hardware- or sequence to prevent those susceptibility-induced signal-dropout. We demonstrated DWI with head-tilting (up to 20°) resulted in had less severe signal dropout and improved image quality than normal scan in the prefrontal cortex.
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