Free-running cardiac DIXON-MRI has potential for T2*/PDFF quantification to explore cardiac fat accumulation and alteration in metabolic diseases. DIXON at 3T suffers from rapid fat-water phase accrual and inhomogeneous B0. Consequently, bipolar echoes, as opposed to monopolar, are required to achieve equal/shorter than in-phase/out-of-phase echo spacing. However, distortions occur between even and odd echoes due to gradients imperfections. Thus, the existing framework was extended with a k-space trajectory correction based on gradient impulse response function(GIRF). Both monopolar or bipolar echoes without GIRF correction resulted in fat-water swaps and unreliable quantitative maps, that were resolved using GIRF-corrected bipolar free-running DIXON.
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