Meeting Banner
Abstract #1645

In-vivo microstructural characterisation of first and higher order thalamic nuclei: a diffusion kurtosis imaging study

Sebastian Hübner1, Lisa Novello1, Giacomo Tomezzoli1, and Jorge Jovicich1
1CIMeC, Center for Mind/Brain Sciences, University of Trento, Rovereto (Trento), Italy


The thalamus is a primary station for information processing within the brain. It is composed of a collection of nuclei with different histological and functional properties, classified as First Order (FO, processing sensory input) or Higher Order (HO, playing associative roles). We used diffusion-weighted MRI (dMRI) to investigate microstructural properties of FO and HO thalamic nuclei, focusing on fractional anisotropy, mean diffusivity, and mean kurtosis derived from Diffusion Kurtosis Imaging (DKI). This initial evidence suggests that DKI might capture distinctive features of FO and HO thalamic nuclei, and paves the way to further studies investigating nucleus-specific microstructural effects with DKI.

This abstract and the presentation materials are available to members only; a login is required.

Join Here