Left atrial late gadolinium enhancement imaging is a promising tool to identify scar and fibrosis. Existing acquisition and reconstruction methods can suffer from long scan time, poor image quality, and inability to accurately quantify the fibrosis. Here we propose a fixed time isotropic imaging of the left atrium with a resolution of 1.25mm3. We use retrospective respiratory navigation to remove inconsistent data due to motion and use a constrained reconstruction framework with total variation and 3D block-matching regularizers to remove the data undersampling artifacts. Promising results showing gains from the isotropic acquisitions are presented in canine and human studies.
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