Single Breath-hold Simultaneous T2 and TRAFF2 mapping for approximate Spin-lock Dispersion Mapping in the Myocardium at 3T
Joao Tourais1, Omer Burak Demirel2, Qian Tao3, Iain Pierce4, George Thornton4, Thomas Treibel4, Sebastian Weingärtner1, and Mehmet Akcakaya2
1Imaging Physics, Delft University of Technology (TU Delft), Delft, Netherlands, 2Department for Electrical and Computer Engineering, and Center for Magnetic Resonance Research, University of Minnesota, Minnesota, MN, United States, 3Delft University of Technology (TU Delft), Delft, Netherlands, 4Barts heart centre, Barts Health NHS Trust, London, United Kingdom
Spin-lock dispersion is a promising biomarker for the assessment of myocardial infarction. However, at 3T, the required range of T1⍴ maps acquired at different amplitudes suffers from specific absorption rate (SAR) limitations and off-resonance artifacts. Relaxation Along a Fictitious Field (RAFF) is an alternative to SL preparations with lower SAR requirements while still sampling relaxation in the rotating frame. Thus, a single breath-hold simultaneous TRAFF2 and T2 mapping sequence is proposed for sl dispersion mapping at 3T. High visual quality maps and accurate T2, TRAFF2, and SL dispersion values are achieved with the proposed sequence in phantoms and in vivo.
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