Abstract #1668

A groupwise registration & tractography framework for cardiac architecture description by diffusion MRI: application to ventricular junctions

Julie Magat^1,2,3, Maxime Yon^1,2,3, Yann Bihan-Poudec⁴, and Valéry Ozenne^1,2,3,5

¹IHU Liryc, Electrophysiology and Heart Modeling Institute, Foundation Bordeaux Université, Bordeaux, France, ²Univ. Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, ³INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, ⁴Institut des Sciences Cognitives Marc Jeannerod, CNRS UMR 5229, Université Claude Bernard Lyon I, Bron, France, ⁵Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Université de Bordeaux, Bordeaux, France

Synopsis

In this study, we developed a groupwise registration and tractography framework to investigate the global myofiber arrangement of large mammalian sheep hearts. To demonstrate the potential application of the proposed method, a novel description of sub-regions in the intraventricular septum (IVS) is presented. The study focuses on one fiber-bundle in the posterior junction and three fiber-bundles in the anterior junction.

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