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Abstract #1668

A groupwise registration & tractography framework for cardiac architecture description by diffusion MRI: application to ventricular junctions

Julie Magat1,2,3, Maxime Yon1,2,3, Yann Bihan-Poudec4, and Valéry Ozenne1,2,3,5
1IHU Liryc, Electrophysiology and Heart Modeling Institute, Foundation Bordeaux Université, Bordeaux, France, 2Univ. Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, 3INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, 4Institut des Sciences Cognitives Marc Jeannerod, CNRS UMR 5229, Université Claude Bernard Lyon I, Bron, France, 5Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, CNRS/Université de Bordeaux, Bordeaux, France

Synopsis

In this study, we developed a groupwise registration and tractography framework to investigate the global myofiber arrangement of large mammalian sheep hearts. To demonstrate the potential application of the proposed method, a novel description of sub-regions in the intraventricular septum (IVS) is presented. The study focuses on one fiber-bundle in the posterior junction and three fiber-bundles in the anterior junction.

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