Self organization of breath-hold induced cerebrovascular BOLD fMRI responses reveals physiologically-driven brain parcellation and networks
Stefano Moia1, Molly G Bright2,3, and César Caballero-Gaudes1
1Basque Center on Cognition, Brain and Language, Donostia, Spain, 2Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, 3Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, United States
Recent literature brought up the existence of physiological and vascular brain networks, i.e. areas showing synchronous responses to cardiac and respiratory fluctuations or hypercapnia. In this work, we show how breath-hold-induced BOLD fMRI time series from a dense mapping dataset can be parcellated into physiologically-driven networks, showing evidence of vascular contributions to the default mode network, in individuals and at the group level.
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