Abstract #1676

Self organization of breath-hold induced cerebrovascular BOLD fMRI responses reveals physiologically-driven brain parcellation and networks

Stefano Moia¹, Molly G Bright^2,3, and César Caballero-Gaudes¹

¹Basque Center on Cognition, Brain and Language, Donostia, Spain, ²Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ³Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL, United States

Synopsis

Recent literature brought up the existence of physiological and vascular brain networks, i.e. areas showing synchronous responses to cardiac and respiratory fluctuations or hypercapnia. In this work, we show how breath-hold-induced BOLD fMRI time series from a dense mapping dataset can be parcellated into physiologically-driven networks, showing evidence of vascular contributions to the default mode network, in individuals and at the group level.

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