Abstract #1680
In vivo mapping of sodium relaxation times in breast fibroadenoma at 7T
Carlotta Ianniello1,2, Ryan Brown1,2, Linda Moy1,2,3, Justin Fogarty1, Freya Schnabel3,4, Deborah Axelrod3,4, and Guillaume Madelin1,2
1Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 3Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY, United States, 4Department of Surgery, New York University Grossman School of Medicine, New York, NY, United States
Synopsis
Sodium (23Na) MRI has been employed to measure the total sodium concentration (TSC) in breast lesions, which is often elevated compared to healthy breast. The knowledge of the 23Na relaxation times of the breast, which could be subject to variations in lesions, could increase the accuracy of TSC estimation. In this work we measured the 23Na relaxation times in six fibroadenoma patients and found a 71% increase in T2,s and a 28% decrease in T1 in the lesions compared to healthy tissue. Therefore, using healthy breast relaxation times in TSC quantification could result in errors in lesions.
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