Abstract #1679

Discrimination Between Benign and Malignant Lesions in the Breast with Restriction Spectrum Imaging on a Screening Breast MRI Cohort

Stephane Loubrie¹, Ana Rodriguez-Soto¹, Lauren Fang¹, Christopher Conlin¹, Maren MS Andreassen², Tyler Seibert^1,3,4, Michael Hahn¹, Vandana Dialani^5,6, Catherine J Wei⁷, Zahra Karimi⁵, Joshua Kuperman¹, Anders Dale^1,8, Etta Pisano^5,9, and Rebecca Rakow-Penner^1,4

¹Radiology, UCSD, San Diego, CA, United States, ²Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, ³Radiation medecine, UCSD, San Diego, CA, United States, ⁴Bioengineering, UCSD, San Diego, CA, United States, ⁵Beth Israel Hospital, Boston, MA, United States, ⁶Harvard Medical School, Bosston, MA, United States, ⁷Commonwealth Radiology Associates, Boston, MA, United States, ⁸Neurosciences, UCSD, San Diego, CA, United States, ⁹American college of radiology, Reston, VA, United States

Synopsis

Diffusion weighted imaging (DWI) holds great potential in improving specificity of findings detected on contrast enhanced breast MRI. Restriction spectrum imaging (RSI), an advanced diffusion imaging model, has potential in discriminating between malignant and fibroglandular breast tissue. In this abstract, we evaluate RSI’s performance in differentiating malignant from benign lesions in a prospective study performed on a breast screening population. All lesions were biopsy proven. The breast RSI model allowed discrimination between malignant, high-risk and low-risk benign lesions and healthy fibroglandular tissue.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.