Meeting Banner
Abstract #1744

Increased Iron Deposition in Gray Matter Nuclei in Patients with Intracranial Artery Stenosis Evaluated by Quantitative Susceptibility Mapping

Huimin Mao1, Weiqiang Dou2, Xinyi Wang1, Kunjian Chen1, and Yu Guo1
1Radiology, The First Affiliated Hospital of Shandong First Medical University, Jinan, China, 2MR Research China, GE Healthcare, Beijing, China


This study aimed to use quantitative susceptibility mapping (QSM) to systematically investigate iron content changes of gray matter (GM) nuclei in patients with long-term anterior circulation artery stenosis (ACAS) and posterior circulation artery stenosis (PCAS). The differences of iron-related susceptibility in GM nuclei, including bilateral caudate nucleus, putamen (PU), globus pallidus (GP), thalamus, substantia nigra (SN), red nucleus and dentate nucleus (DN) were explored in 25 ACAS and 25 PCAS patients. Compared with healthy controls, mean susceptibility of bilateral PU, GP, and SN in ACAS and PCAS patients, and of extra bilateral DN in PCAS patients were significantly increased.

This abstract and the presentation materials are available to members only; a login is required.

Join Here