MULTI-CONTRAST ATHEROSCLEROSIS CHARACTERIZATION (MATCH) AND MULTI-SEQUENCE MRI IN QUANTIFYING CAROTID PLAQUE COMPOSITION
Mohamed Kassem1,2, Ellen Eline Boswijk1,2, Jochem van der Pol1,2, Rik PM Moonen2, Jan Bucerius3, Werner H Mess4, Robert Jan van Oostenbrugge1,5, Zhaoyang Fan6, and M Eline Kooi1,2
1CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands, Maastricht, Netherlands, 2Department of Radiology and Nuclear Medicine, Maastricht University medical center (MUMC+), Maastricht, Netherlands, 3Department of Nuclear Medicine, Georg-August University Göttingen, Gottingen, Germany, 4Department of Clinical Neurophysiology, Maastricht University medical center (MUMC+), maastricht, Netherlands, 5Department of Neurology, Maastricht University Medical Center+ (MUMC+), maastricht, Netherlands, 6Department of Radiology, University of Southern California, Los Angeles, CA, United States
Multi-contrast Atherosclerosis Characterization (MATCH) was developed to quantify of carotid atherosclerotic plaque composition within 5 minutes’ scan time. Twenty symptomatic patients with ≥2 mm carotid plaque underwent 3.0 Tesla conventional multi-sequence and MATCH MRI. Excellent agreement was obtained for scoring a Lipid-rich necrotic core (LRNC) intraplaque hemorrhage (IPH) on the MATCH images while fair for calcifications. No significant differences between MATCH and multi-sequence MRI were found in volume of LRNC, IPH and calcifications. We demonstrated excellent agreement between MATCH and multi-sequence MRI for the identification and quantification of LRNC and IPH within significant shorter time.
This abstract and the presentation materials are available to members only;
a login is required.