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Abstract #1756

Self-calibrated through-time spiral GRAPPA for real-time, free-breathing evaluation of left ventricular function

Dominique Franson1, James Ahad1, Yuchi Liu2, Alexander Fyrdahl2, and Nicole Seiberlich2
1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2University of Michigan, Ann Arbor, MI, United States


Through-time non-Cartesian GRAPPA enables real-time, free-breathing evaluation of the left ventricle, but it requires extra calibration data. This work proposes a self-calibrated spiral GRAPPA method that uses an interleaved acquisition to eliminate the calibration scan. A long spiral trajectory is used to improve robustness to motion. Data were acquired at 12 LV slices with spatiotemporal resolutions of 2.08x2.08 mm2 and 32.72 ms/phase in 71 seconds. In a preliminary study of 6 volunteers comparing the proposed method to a gold-standard, functional values are within the limits of agreement in Bland-Altman analyses and are not statistically significantly different in paired t-tests (p<0.05).

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