ParaHydrogen Induced Polarization is a hyperpolarization method much less technically demanding and affordable than d-DNP. The Side Arm Hydrogenation method allowed to obtain hyperpolarized [1-13C]pyruvate that can be used for metabolic studies, but concerns about the safety and bio-compatibility of the final aqueous solution of the HP products may be present, due to organic solvents and metal complex. In this work, a method to remove all the traces of toxic solvents and metal complex from the final product will be presented, together with the 13C-MR images obtained using the metabolite thus hyperpolarized.
This abstract and the presentation materials are available to members only; a login is required.