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Abstract #1889

The Effect of Differences in MRS Parameters on Data Harmonization of Normative Data

Marcia Sahaya Louis1,2, Huijun Vicky Liao2, Ajay Joshi1, and Alexander Lin2
1ECE, Boston University, Boston, MA, United States, 2Radiology, Brigham and Women's Hospital, Boston, MA, United States


Building normative databases for MR spectroscopy studies is much needed to further the use of MRS in large clinical studies. The effect of differences in MRS parameters is not well documented and there are no established data harmonization methods for MRS data. Therefore, the goal of this study is to identify the effects of variations such as dwell time, coil type, and software version and describe a method for harmonizing data in healthy controls that will ameliorate those effects.

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