Abstract #1890

Integrating hybrid CSI/EPSI acquisitions with L2 regularization for lipid removal of MRSI

Yiling Liu¹, Jianfeng Bao², Hao Chen¹, Guiqin Liu³, Jingliang Chen², and Zhiyong Zhang¹

¹School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, ²The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China, ³Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai Jiao Tong University, Shanghai, China

Synopsis

Placements of lipid saturation bands not only demand a skillful MRSI scanning operation but also restrict the full brain MRSI coverage. Therefore, MRSI acquisition without lipid suppression while doing post-removal of lipid becomes clinically attractive and valuable. In this work, we propose to integrate hybrid CSI/EPSI acquisitions with L2 regularization for fast lipid removal of MRSI. The hybrid CSI/EPSI acquisitions rely on the same excitation and refocusing evolution with the modified CSI and EPSI sequences. Phantom and in-vivo brain studies demonstrate the effectiveness and low computational cost of the proposed method.

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