Abstract #1891
semi-LASER MRS at 3T with TR=5s: All the Signal, Similar Scan Time, and Minimal T1 Weighting
Alex Ensworth1,2, Laura R. Barlow3,4, Piotr Kozlowski1,2,3,4, Erin L. MacMillan3,4,5, and Cornelia Laule1,2,3,6
1Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 2International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, BC, Canada, 3Radiology, University of British Columbia, Vancouver, BC, Canada, 4UBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada, 5Philips Canada, Mississauga, ON, Canada, 6Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
Synopsis
The choice of repetition time (TR) in MR spectroscopy studies is widely debated. A shorter TR results in more clinically acceptable scan times, however due to T1 effects, the metabolite concentrations are reduced. We used semi-LASER MRS to compare the SNR and absolute metabolite concentrations for TR=2,5 and 8s. We demonstrate it is possible to achieve similar SNR and scan time using a TR of 5s with half the acquisitions compared to a TR of 2s, where the metabolite concentrations are 20% lower. Using a TR of 5s for any MRS study is feasible and recommended to minimize T1 effects.
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