Abstract #1915

High Resolution Postmortem Brain Imaging at 7 Tesla using Parallel Transmission and a Simple Set-Up

Eberhard Daniel Pracht¹, Markus Cremer², Daniel Loewen¹, Franck Mauconduit³, Aurelien Massire⁴, Sebastian Bludau², Nicolas Boulant³, Katrin Amunts^2,5, and Tony Stoecker^1,6

¹German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, ²Institute for Neuroscience and Medicine, INM-1, Structural and Functional Organisation of the Brain, Forschungszentrum Juelich GmbH, Juelich, Germany, ³University of Paris-Saclay, CEA, CNRS, BAOBAB, NeuroSpin, Gif sur Yvette, Paris-Saclay, France, ⁴Siemens Healthcare SAS, Saint-Denis, France, ⁵Cecile and Oskar Vogt Institute for Brain Research, Heinrich Heine University Duesseldorf, University Hospital, Duesseldorf, Germany, ⁶Department of Physics and Astronomy, University of Bonn, Bonn, Germany

Synopsis

In this work we present a simple set-up for high resolution postmortem imaging at ultra high field strength. The processed images have high, as well as homogeneous gray/white matter contrast over the whole brain. Additionally, during post-processing, the background signal of the fixation liquid is almost completely removed, allowing for an optimal image registration process after histological sectioning.

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