High Resolution Postmortem Brain Imaging at 7 Tesla using Parallel Transmission and a Simple Set-Up
Eberhard Daniel Pracht1, Markus Cremer2, Daniel Loewen1, Franck Mauconduit3, Aurelien Massire4, Sebastian Bludau2, Nicolas Boulant3, Katrin Amunts2,5, and Tony Stoecker1,6
1German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 2Institute for Neuroscience and Medicine, INM-1, Structural and Functional Organisation of the Brain, Forschungszentrum Juelich GmbH, Juelich, Germany, 3University of Paris-Saclay, CEA, CNRS, BAOBAB, NeuroSpin, Gif sur Yvette, Paris-Saclay, France, 4Siemens Healthcare SAS, Saint-Denis, France, 5Cecile and Oskar Vogt Institute for Brain Research, Heinrich Heine University Duesseldorf, University Hospital, Duesseldorf, Germany, 6Department of Physics and Astronomy, University of Bonn, Bonn, Germany
In this work we present a simple set-up for high resolution postmortem imaging at ultra high field strength. The processed images have high, as well as homogeneous gray/white matter contrast over the whole brain. Additionally, during post-processing, the background signal of the fixation liquid is almost completely removed, allowing for an optimal image registration process after histological sectioning.
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