A radiomics approach to assess high risk carotid plaques: a non-invasive imaging biomarker, retrospective study
Sihan celestine Chen1, Yunfei Zha2, Changsheng Liu2, Xixiang chen3, Ling ma4, and Weiyin vivian Liu5
1Radiology, Renmin Hospital of Wuhan University and Hubei General Hospital, Wuhan, China, 2Radiology, enmin Hospital of Wuhan University and Hubei General Hospital, Wuhan, China, 3Renmin Hospital of Wuhan University and Hubei General Hospital, Wuhan, China, 4He Kang Corporate Management (SH) Co.Ltd, Shanghai, China, Wuhan, China, 5Advanced Application specialist, GE Healthcare, Beijing, China, Beijing, China
This study aimed to construct a radiomics-based T2-weighted imaging (T2WI) approach from high-resolution multi-contrast magnetic resonance imaging (hrMRI) in combination with clinical high-risk factors for non-invasive assessment, to differentiate symptomatic carotid atherosclerotic plaques from asymptomatic ones. Radscore showed a better diagnostic performance. The combination model of texture features and clinical data had the best performance in assessment of lesion vulnerability. This study demonstrated that hrMRI radiomics features provided incremental value for assessment of the carotid atherosclerotic vulnerability.
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