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Abstract #1922

Frailty assessment using synthetic MRI

Di Wang1, Chunmei Li2, Yuhui Chen2, Pu-Yeh Wu3, and Min Chen1
1Beijing Hospital, National Center of Gerontology; Institute of Geriatric Me, Beijing, China, 2Beijing Hospital, Beijing, China, 3GE Healthcare, Beijing, China, Beijing, China


Synthetic MRI is a novel method which can provides quantitative relaxation mapping and synthetic contrast-weighted images at the same time. In this study, we adopted this technique to assessed the frailty. We found T2 relaxation of right insular lobe and right limbic subcortical nuclei had significant difference between frailty and prefrailty patients. T1 and T2 relaxation of right limbic subcortical nuclei and right basal ganglia significantly correlated with the short physical performance battery total scores. Overall, our findings suggested the synthetic MR can be considered an effective tool for assessing frailty.

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