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Abstract #1936

Diagnostic performance of histological fibrous capsule and pseudocapsule (a false-positive fibrous capsule) in hepatocellular carcinoma

Atsushi Higaki1, Akira Yamamoto1, Takeshi Fukunaga1, Hirotake Nishimura2, Akihiko Kanki1, and Tsutomu Tamada1
1Radiology, Kawasaki Medical School, Kurashiki, Japan, 2Pathology, Kawasaki Medical School, Kurashiki, Japan

Synopsis

We used contrast-enhanced MRI and CT to evaluate the diagnostic potential of histological fibrous capsule and pseudocapsule in HCC. 51.4% (36/70) of HCCs had capsules, and pseudocapsule was found in 35.3% (18/51) of lesions with enhancing capsule imaging. Among the various imaging features, T1WI low signal rim, arterial phase low signal capsule, enhancing capsule on MRI and CT, and tumor margin enlargement sign on HBP were useful in diagnosing fibrous capsules. Among these, tumor margin enlargement sign on HBP showed the highest accuracy for the diagnosis of capsule, and was the only finding that could diagnose pseudocapsule.

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