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Abstract #1941

Does Functional Parameters from Gadoxetic Acid–enhanced MRI Predict Decompensation in Cirrhosis?

Xueqin ZHANG1, Tao ZHANG1, Lei XU1, and Xiance ZHAO2
1Affiliated Nantong Hospital 3 of Nantong University, Nantong, China, 2Philips Healthcare, Shanghai, China


We used Look-Locker sequences to acquire T1 mapping images pre and post-contrast at 20 minutes after gadoxetic acid administration. Liver-to-spleen contrast index (LSI), contrast uptake index (CUI), relative liver enhancement (RLE), hepatocyte fraction (HeF), T1 relaxation times on unenhanced phase (T1unenh), T1 relaxation times on hepatobiliary phase (T1HBP), reduction rates of T1 relaxation times (rrT1), and the functional liver imaging score (FLIS) of the liver were measured and calculated by two radiologists independently. Our study showed that LSI, CUI, HeF, T1HBP, rrT1 and FLIS based on gadoxetic acid–enhanced MRI are help for the evaluation of liver function.

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