The goals of this study were to investigate the effect of alcohol usage on scyllo-inositol (sIns) in young and older healthy adults, and measure the T2 of sIns in young and older healthy adults. Two brain regions (occipital cortex (OCC), posterior cingulate cortex (PCC)) were studied at 3T. sIns was measured using a short-echo-time STEAM while T2 was measured using LASER. sIns in OCC and PCC regions was found to increase as the brain ages; alcohol usage (0-2 drinks/week) was significantly different between age groups. In addition, there seems to be a trend towards lower T2 of sIns with age.
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