Abstract #1944

Sex-specific differences in the relationships between obesity, cerebral perfusion and grey matter volume

Brittany Intzandt^1,2,3,4, Safa Sanami^2,4,5, Julia Huck^4,5, Rick D Hoge⁶, PREVENT-AD Research Group⁷, Louis Bherer ^2,3,8, and Claudine J Gauthier^2,4,5

¹School of Graduate Studies, Concordia University, Montreal, QC, Canada, ²Centre EPIC, Montreal Heart Institute, Montreal, QC, Canada, ³Centre de Recherche de l’Institut Universitaire de Geriatrie de Montreal, Montreal, QC, Canada, ⁴PERFORM Centre, Concordia University, Montreal, QC, Canada, ⁵Department of Physics, Concordia University, Montreal, QC, Canada, ⁶Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada, ⁷StoP-AD Centre, Douglas Mental Health Institute Research Centre, Montreal, QC, Canada, ⁸Department of Medicine, University of Montreal, Montreal, QC, Canada

Synopsis

Cerebral health declines in aging. Obesity is reported to accentuate, reduce or have no effect on these declines. Given sex differences are present for cerebral health and obesity individually, it is hypothesized these discrepancies are influenced by sex. Here, we investigated the relationship between obesity, cerebral structure and perfusion in aging females and males separately. Females revealed greater obesity was associated with increased structure and perfusion. Males demonstrated a positive relationship with obesity and perfusion, however, an inverse association was identified between structure and obesity. Future work should investigate the influence of other lifestyle factors on these sex-specific relationships

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.