Meeting Banner
Abstract #1947

Peri-tumoural distribution of lipid composition in postmenopausal patients with oestrogen receptor positive breast cancer

Sai Man Cheung1, Kwok-Shing Chan1,2, Wenshu Zhou1, Ehab Husain3, Tanja Gagliardi1,4, Yazan Masannat5, and Jiabao He1
1Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom, 2Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands, 3Pathology Department, Aberdeen Royal Infirmary, Aberdeen, United Kingdom, 4Radiology Department, Royal Marsden Hospital, London, United Kingdom, 5Breast Unit, Aberdeen Royal Infirmary, Aberdeen, United Kingdom

Synopsis

Early diagnosis is crucial for the prognosis of patients with breast cancer. Postmenopausal women with oestrogen receptor positive cancer account for over half of all new diagnosis, with an imbalance of lipid composition in peri-tumoural adipose tissue. Since oestrogen is primarily modulated by mammary adipocytes, lipid composition monitoring for early sign of heterogeneous lipid deregulation is central to the accurate early detection. Novel chemical shift-encoded imaging (CSEI) allows rapid lipid mapping of whole breast. We set out to elucidate the spatial distribution in the deregulation of peri-tumoural lipid composition in postmenopausal patients with oestrogen receptor positive breast cancer using CSEI.

This abstract and the presentation materials are available to members only; a login is required.

Join Here