Hyperpolarized 13C spectroscopic images are acquired at a low spatial resolution, making it necessary to apply superresolution techniques to the metabolite maps prior to fusion with the proton anatomic image for visualization of metabolite biodistribution. In this work, we demonstrate great improvement in image quality for preclinical and clinical images when the metabolite map is upsampled by high spatial frequency transfer from magnetic resonance images of thermally polarized 13C phantoms to the invivo metabolic image.
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