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Abstract #1963

Learning motion correction from YouTube for real-time MRI reconstruction with AUTOMAP

David E J Waddington1, Christopher Chiu1, Nicholas Hindley1,2, Neha Koonjoo2, Tess Reynolds1, Paul Liu1, Bo Zhu2, Chiara Paganelli3, Matthew S Rosen2,4,5, and Paul J Keall1
1ACRF Image X Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia, 2A. A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 3Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy, 4Department of Physics, Harvard University, Cambridge, MA, United States, 5Harvard Medical School, Boston, MA, United States

Synopsis

Today’s MRI does not have the spatio-temporal resolution to image the anatomy of a patient in real-time. Therefore, novel solutions are required in MRI-guided radiotherapy to enable real-time adaptation of the treatment beam to optimally target the cancer and spare surrounding healthy tissue. Neural networks could solve this problem, however, there is a dearth of sufficiently large training data required to accurately model patient motion. Here, we use the YouTube-8M database to train the AUTOMAP network. We use a virtual dynamic lung tumour phantom to show that the generalized motion properties learned from YouTube lead to improved target tracking accuracy.

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