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Abstract #2039

The feasibility of DCE-MRI in presurgical evaluation of tumor budding grade in rectal cancer

Wenjun Hu1, Anliang Chen2, Wan JUN Dong2, Xiwei JUN Li2, Yue Wang2, Yuhui Liu2, and Ailian Liu1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, 2The First Affiliated Hospital of Dalian Medical University, Dalian, China


Tumor budding (TB) is a histopathologic characteristic which has led to a growing interest in the prognosis prediction of cancers of various sites. Preoperative prediction of TB status may help personalize treatment in rectal cancer cancer patients. Previous studies showed MRI-based and PET/CT based radiomics can predict TB status, however, the high cost and complex post-processing limit their clinical applications. Dynamic contrast-enhanced (DCE) MRI has been extensively evaluated aggressiveness of rectal cancer. Results of this study indicate Kep values can effectively differentiate high from intermediate-low grade TB.

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