Abstract #2045

**Increased liver stiffness and shortened T2* relaxation time in people with type 2 diabetes**

Yuliya Kupriyanova^1,2, Pavel Bobrov^2,3, Volker Burkart^1,2, Vera Schrauwen-Hinderling^1,2,4, and Michael Roden^1,2,5

¹Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany, ²German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Germany, ³Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany, ⁴Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, Netherlands, ⁵Department of Endocrinology and Diabetology, Medical Faculty and University Hospital, Heinrich Heine University, Düsseldorf, Germany

Synopsis

This study shows the value of multiparametric magnetic resonance measurements for detecting the changes in liver tissue due to diabetes mellitus. Liver fat content (determined by mDixon MRI and ¹H-MR spectroscopy), T2* relaxation time and liver stiffness were compared in humans with type 1 (T1DM), type 2 diabetes mellitus (T2DM) or normal glucose tolerance (control, CON).

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