Diabetes mellitus is significantly associated with posterior circulation ischemic stroke. We aimed to compare the characteristics of vertebrobasilar plaques in symptomatic patients with and without diabetes using vessel wall magnetic resonance imaging and computed tomographic angiography. Characteristics of symptomatic vertebrobasilar plaques were compared between patients with and without diabetes. Multivariate analysis demonstrated differences in the presence of T1 hyperintensity and number of spotty calcifications were statistically significant. Symptomatic patients with diabetes have a higher incidence of T1 hyperintensity and larger calcification burden than those without diabetes, indicating the association of diabetes with more advanced plaque features in the posterior circulation.
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