Spirometry is a standard exam in pulmonary function testing for assessing the efficiency of global ventilation from flow-volume loops measured at the mouth during forced respiratory cycles. A newly developed technique, 3D MR spirometry, makes use of dynamic magnetic resonance imaging during spontaneous breathing to produce regional characterization of the lung function. The sensitivity of the technique was challenged with respect to gravity by extracting the associated ventilation gradients in prone and supine healthy volunteers.
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