Abstract #2065

3D super-resolution MR elastography of the brain

Simone Hufnagel¹, Matthias Anders², Christoph Stefan Aigner¹, Helge Herthum², Heiko Tzschaetzsch², Tobias Schaeffter^1,3,4, Ingolf Sack², and Christoph Kolbitsch¹

¹Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, ²Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ³School of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, ⁴Department of Biomedical Engineering, Technical University of Berlin, Berlin, Germany

Synopsis

MR elastography (MRE) provides valuable quantitative information about the mechanical properties of brain tissues. However, due to SNR limitations, often only low through-plane resolution is possible. We present super-resolution MRE based on multiple stacks of complex 3D wavefields of the brain resulting in elastograms with isotropic (1×1×1) mm³ resolution. The approach was evaluated for the in-vivo brain and showed improved visibility of fine structures while presenting consistent shear wave speed values.

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