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Abstract #2081

Repeatability of B1 Inhomogeneity Correction of Volumetric (3D) Glutamate CEST via High-Permittivity Dielectric Padding at 7T

Paul Samuel Jacobs1, Ravi Prakash Reddy Nanga1, Abigail Cember1, Dylan M Tisdall2, Sandhitsu Das3, John Detre1,3, David Roalf4, and Ravinder Reddy1
1CAMIPM, Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2Radiology, University of Pennsylvania, Philadelphia, PA, United States, 3Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States, 4Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, United States

Synopsis

Dielectric pads were used to improve the contrast of volumetric (3D) gluCEST via enhanced homogenization of B1 fields. Effective placement of the pads required additional coverage of the face due to their physical size to achieve the saturated B1 strength necessary to recover the gluCEST signal from the anterior portions of the brain. The origin of gluCEST's need for high B1 is discussed, and examples of 3D gluCEST images acquired with and without the use of the dielectric pads are provided and repeatability of the 3D gluCEST in the presence of pad placement was determined.

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