Sodium studies have shown subtle pathophysiologic changes in tissue sodium concentrations (TSC) in the early stage of the various diseases. One of the major challenges with measuring TSC is its low SNR. Phased array coils are used to increase sodium SNR, however, they result in an inhomogeneous receive profile that makes accurate quantitation of TSC difficult. Uniformity correction is thus required and is often done by generating a sensitivity map. A previous approach introduced the concept of utilizing a universal sensitivity map to reduce total scan time. We present an improved universal sensitivity map solution.
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