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Abstract #2092

Parallel Transmit DANTE-SPACE for improved black-blood signal suppression at 7 Tesla

Matthijs H.S. de Buck1, James L. Kent1, Aaron T. Hess1, and Peter Jezzard1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom


DANTE-SPACE can be used for visualizing intracranial vessel walls at 7T, where the flow-sensitive signal attenuation of the DANTE preparation simultaneously suppresses signal from the internal blood and external CSF. However, the efficacy of DANTE is reduced for blood moving upstream through the neck due to limited B1+ coverage at 7T. Here, EPG simulations are used to estimate the effect of this limited B1+ coverage on the achieved contrasts. A pTx-based approach which uses separate RF shims for the DANTE-preparation and the SPACE readout to improve the attenuation of blood moving through the neck is proposed, and validated in vivo.

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