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Abstract #2102

Investigation of the inferior fronto-occipital fasciculus in the macaque fascicularis brain using 11.7 T ultra-high field diffusion data

Maëlig Chauvel1, Ivy Uszynski1, Clara Fischer1, Fabrice Poupon1, Christophe Destrieux2, Igor Maldonado2, and Cyril Poupon1
1BAOBAB, NeuroSpin, Université Paris-Saclay, CNRS, CEA, Gif-sur-Yvette, France, 2Unité Imagerie & Cerveau (iBrain), UMRS INSERM 1253, Université de Tours, Tours, France


In this study, we investigated the controversial presence of the inferior fronto-occipital fasciculus (IFOF) in the macaque species (Macaca fascicularis) using ultra-high field MRI (11.7 T) diffusion data. Thanks to a fiber clustering approach, we were able to reconstruct the IFOF in both hemispheres. We observed thin frontal connections and a more developed fasciculus on the right hemisphere compared to the left. The presence of this special fasciculus, known in Humans as being part of the ventral pathways for multi-modal language processing, is a new step forward concerning the comprehension of the macaque brain, and the primate brain in general.

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