Proof of concept of volumetric MR-temperature monitoring during microwave ablation of liver tumor in a patient
Pierre Bour1, Thibaut Faller1, Valery Ozenne2,3,4, Bruno Quesson2,3, Max Seidensticker5, and Olaf Dietrich5
1Certis Therapeutics, Pessac, France, 2INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, Bordeaux, France, 3IHU Liryc, Electrophysiology and Heart Modeling Institute, Hopital Xavier Arnozan, Pessac, France, 4UMR5536 CRMSB, Bordeaux, France, 5Department of Radiology, University Hospital, LMU Munich, Munich, Germany
Microwave tumor ablation in the liver is commonly performed in computed tomography scanners with limited imaging capability for real-time monitoring of treatment progression. Performing this procedure under MRI enables to monitor temperature and thermal dose during the ablation. It allows better understanding of the lesion creation and gives better insight of the treatment outcome. In this study, we evaluate a complete MR-guided workflow that include volumetric temperature and dose monitoring during ablation using an ultrafast EPI sequence with respiratory triggering. Results show that spatial extent of the lesion can be monitored and displayed in real-time.
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