Shutter Speed Model (SSM) based Ktrans, ve, kep, and τi in the pancreatic tumors before initiating chemotherapyt were 0.081±0.036 mm-1, 0.258±0.070, 0.320±0.152 mm-1, and 0.247±0.197 μs, respectively, without statistical difference between the responding and non-responding groups. The Ktrans in the tumors favorably responding to chemotherapy increased 72±14%, significantly larger than in the non-responding tumors (2±9%, p=0.0001). The ve in the responding tumors also significantly increased compared to the non-responding group (64±25% vs 3±9%, p=0.0036). However, no statistical difference was found between the responding and non-responding groups in either kep (6±11% vs 11±16%, p=0.6204) or τi (3±47% vs 147±280%, p=0.3408).
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