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Abstract #2138

Intraoperative MRI-derived 3D ablation margins and correlation with local outcome after MRI-guided cryoablation of small renal tumors

Nienke S. de Jager1, Tim J. van Oostenbrugge2, Torben Pätz3, Sjoerd F.M. Jenniskens1, Jurgen J. Fütterer1, Hans Langenhuijsen2, and Christiaan G. Overduin1
1Medical Imaging, Radboudumc, Nijmegen, Netherlands, 2Urology, Radboudumc, Nijmegen, Netherlands, 3Fraunhofer Institute for Digital Medicine, Bremen, Germany


MRI-guided cryoablation of small renal tumors relies on achieving sufficient ice ball coverage throughout the entire lesion for effective treatment. However, a volumetric approach to assess treatment margins intraoperatively is currently lacking. This work retrospectively derived three-dimensional ablation margins after cryoablation in 39 kidney tumors using co-registration of intraoperatively acquired pre- and post-ablation MR images. Minimal ablation margins were significantly smaller for cases with versus without local tumor progression. Radiological complete coverage (ablation margin >0 mm) was associated with local control. MRI-derived 3D ablation margins may present a useful intraprocedural tool to assess treatment success.

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