Abstract #2137
Initial Observations on the Association of Peri-prostatic Vascular Asymmetry and Extra-prostatic Extension of Prostatic Tumors
Paul E Summers1, Alessia Minchillo2, Sarah Alessi1, Giuseppe Renne3, Ottavio De Cobelli4,5, Gennaro Musi4,5, Giulia Marvaso4,6, Barbara Alicja Jereczek-Fossa4,6, and Giuseppe Petralia4,7
1Division of Radiology, IEO, European Institute of Oncology IRCCS, Milano, Italy, 2University of Milan, Milano, Italy, 3Uropathology and Intraoperative Diagnostics, IEO, European Institute of Oncology IRCCS, Milano, Italy, 4Department of Oncology and Hemato-oncology, University of Milan, Milano, Italy, 5Division of Urology, IEO, European Institute of Oncology IRCCS, Milano, Italy, 6Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milano, Italy, 7Precision Imaging and Research Unit, IEO, European Institute of Oncology IRCCS, Milano, Italy
Synopsis
We hypothesized that the presence of asymmetry in the arterial supply of the prostate may provide a correlate of extra-prostatic tumor extension in patients with prostate cancer. In this preliminary study of 40 patients (20 with and 20 without extra-prostatic disease), a radiologist blind to the status of the patients, made a binary choice as to the presence or absence of peri-prostatic vascular asymmetry. Taking the pathological grading as the reference standard, the sensitivity, specificity, positive and negative predictive values were all 0.9. The negative likelihood ratio (LR-) was 0.11, and the positive likelihood ratio (LR+) was 9.0.
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