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Abstract #2147

AI-Assisted Analysis of Iceball Coverage on Patient Outcomes Following MR-guided Focal Cryoablation for Prostate Cancer: A Retrospective Study

Nicholas Fordham1,2, Junichi Tokuda1, Pedro Moreira1, Clare M Tempany1, and Kemal Tuncali1
1Department of Radiology, Brigham and Women's Hospital, Boston, MA, United States, 2Boston University School of Medicine, Boston, MA, United States


We conducted a retrospective study of 44 MRI-guided focal cryoablation cases for prostate cancer. Our goal was to evaluate AI-assisted MRI-based assessment of inadvertent cryoinjuries in the surrounding structures as predictors of post-procedural morbidities. Specifically, we estimated the iceball involvement with the external urethral sphincter (EUS) and the neurovascular bundle (NVB) using intraprocedural T2-weighted MRI and correlated with acute postoperative urinary incontinence and erectile dysfunction. The study demonstrated a correlation between incontinence and MRI-estimated iceball involvement with the EUS. However, no correlation was found between erectile dysfunction and the iceball involvement with the NVB.

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