Platform for Real-Time Multiplane Targeting and Monitoring of Minimally-Invasive Image-Guided Prostate Cryoablation Procedures
Thomas Lilieholm1, Robert Moskwa1, Eugene Ozhinsky2, David A Woodrum3, Walter F Block1,4,5, and Erica M Knavel Koepsel6
1Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 2Radiology, University of California - San Francisco, San Francisco, CA, United States, 3Radiology, Mayo Clinic, Rochester, MN, United States, 4Radiology, University of Wisconsin - Madison, Madison, WI, United States, 5Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States, 6Interventional Radiology, University of Wisconsin - Madison, Madison, WI, United States
Minimally invasive cryoablation is an effective and safe treatment option for localized low- and intermediate-risk prostate cancers. Precisely placed cryoprobes in cancerous regions of the prostate kill malignant cells by freezing local tissues while being less invasive than prostatectomy, and having a shorter treatment cycle than most radiotherapies. For accurate probe placement, MR-image guidance is often employed, coupled with external probe-guiding apparati. We developed a platform that enables a cohesive workflow to register the probe-guiding apparati, facilitate target selection, select and verify probe trajectory, and monitor the prostate in real-time using multiple planes during probe insertion and cryoablation freeze cycles.
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