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Abstract #2173

Fast T1-based MR Thermometry at Low Magnetic Field

Marco Fiorito1, Maksym Yushchenko1, Davide Cicolari2, Mathieu Sarracanie1, and Najat Salameh1
1Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland, 2Department of Physics, University of Pavia, Pavia, Italy

Synopsis

Thanks to the enhanced T1 dispersion and its linear dependence on temperature over the typical hyperthermia range, T1 mapping represents a serious candidate for temperature mapping at low magnetic fields. Nonetheless, T1 acquisitions are typically long and sensitivity if further reduced at low field regimes. Here we propose a Look-Locker-based temperature mapping sequence that takes advantage of the inherently higher signal gathered using a bSSFP approach. Temperatures spanning from 25 to 50°C could be mapped in doped-water samples with a temporal resolution of 20s/slice and with a precision of 2.6±1.9°C.

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