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Abstract #2174

Towards MR-guided Hyperthermia at Low Field: a Proof-of-Concept Investigation

Marco Fiorito1, Mauro Spreiter1, Maksym Yushchenko1, Mathieu Sarracanie1, and Najat Salameh1
1Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland


MR-guided hyperthermia at low magnetic field is challenging due to the inherently low SNR, which typically calls for multiple signal averages. Dedicated coils are crucial at this field regime, to maximise signal acquisition. In this study we built a custom RF coil which integrates a water-based heating system to reproduce hyperthermia conditions in hands. Using a fast T1-mapping sequence, we could successfully monitor the temperature variations generated in a phantom over 120min. A first in vivo employment in a volunteer’s hand at room temperature was also shown, achieving a spatial and temporal resolution compatible with hyperthermia requirements.

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