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Abstract #2200

Thalamic and cortical input layers in the somatomotor cortex detected by laminar fMRI in non-human primates at 7T

Sangyun Kang1, Min-Jun Han1,2, Seong-Gi Kim1,2, and Eunha Baeg1
1IBS Center for Neuroscience Imaging Research, Sungkyunkwan University, Suwon, Korea, Republic of, 2Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of


Laminar fMRI has been increasingly used in humans, but its validity needs to be thoroughly confirmed in primate brains. Here, we investigated thalamic and cortical inputs to the somatomotor cortex in the rhesus monkey by adopting tactile stimulation and electrical microstimulation. Compared to 7T BOLD signals, MION-induced CBV-weighted fMRI faithfully captures input layer activities, like the sensory thalamus input to the middle layer and the dense cortical connections in the superficial layers. Taken together, our CBV-weighted fMRI signals revealed different input layers to the somatomotor cortex with high specificity and sensitivity.

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