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Abstract #2204

Longitudinal brain imaging reveals brain white matter changes after COVID-19 in the UK Biobank

Ivan I. Maximov1,2, Dennis van der Meer2,3,4, Ann-Marie de Lange2,3,5, and Lars T Westlye2,3
1Western Norway University of Applied Sciences, Bergen, Norway, 2NORMENT, Oslo University Hospital, Oslo, Norway, 3University of Oslo, Oslo, Norway, 4Maastricht University, Maastricht, Netherlands, 5Lausanne University Hospital, Lausanne, Switzerland

Synopsis

The COVID-19 pandemic has caused a global health crisis. There are a few indications that this disease has harmful consequences on neurological functioning, besides brain changes following COVID-19 infection have not yet been fully understood. Here, we used UK Biobank (UKB) longitudinal diffusion MRI data acquired before and after COVID-19 tests along the ongoing UKB study. We evaluated brain age gap metrics for the participants with positive and negative test results in order to evaluate COVID-19 consequences on the brain.

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