Abstract #2204

Longitudinal brain imaging reveals brain white matter changes after COVID-19 in the UK Biobank

Ivan I. Maximov^1,2, Dennis van der Meer^2,3,4, Ann-Marie de Lange^2,3,5, and Lars T Westlye^2,3

¹Western Norway University of Applied Sciences, Bergen, Norway, ²NORMENT, Oslo University Hospital, Oslo, Norway, ³University of Oslo, Oslo, Norway, ⁴Maastricht University, Maastricht, Netherlands, ⁵Lausanne University Hospital, Lausanne, Switzerland

Synopsis

The COVID-19 pandemic has caused a global health crisis. There are a few indications that this disease has harmful consequences on neurological functioning, besides brain changes following COVID-19 infection have not yet been fully understood. Here, we used UK Biobank (UKB) longitudinal diffusion MRI data acquired before and after COVID-19 tests along the ongoing UKB study. We evaluated brain age gap metrics for the participants with positive and negative test results in order to evaluate COVID-19 consequences on the brain.

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