Post-acute COVID-19 syndrome (PACS) is an umbrella term for the long-term symptoms and poor quality-of-life that follow acute SARS-CoV-2 viral-infection in up to 7/10 COVID-19 survivors. The mechanistic understanding of PACS remains poorly understood, which stymies treatment decision-making. In a PACS pilot study, we evaluated hyperpolarized 129Xe MRI ventilation defect percent and texture features to measure potential longitudinal changes. There were no significant differences in 129Xe MRI ventilation texture measurements six-months and 12-months after a baseline visit (12 weeks post-infection). PACS participants exhibited abnormal second-order 129Xe MRI ventilation textures and patchy ventilation, relative to healthy controls, 6-12 months post-infection.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords